KMID : 1143820060020020079
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Anxiety and Mood 2006 Volume.2 No. 2 p.79 ~ p.85
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Anxiety and GAVA System
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Yang Jong-Chul
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Abstract
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Anxiety and anxiety disorders are related to many neurotransmitters, such as norepinephrine, serotonine, dopamine, glutamate, and Gamma-aminobutyric acid (GABA). GABA, the main inhibitory neurotransmitter of the CNS, is known to counterbalance the action of the excitatory neurotransmitters and control anxiety. GABA acts on 3 GABA receptor subtypes, , , and . and receptors are oligomeric transmembrane glycoproteins composed of 5 subunits that are arranged around a central chloride channel. receptor comprises two 7-transmembraneis-spanning proteins that are coupled to either calcium or potassium channel via G proteins. This article highlights neurobiological interactions between anxiety and GABA system.
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KEYWORD
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Anxiety, GAVA, Neurotransmitter
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